York, I.A., N. Bhutani, S. Zendzian, A.L. Goldberg, and K.L. Rock.
Tripeptidyl peptidase II (TPPII) is the major peptidase needed to trim
long antigenic precursors, but is not required for most MHC class I
antigen presentation.
Journal of Immunology (2006) 177:1434-1443
York, I.A., M.A. Brehm, S. Zendzian, C.F. Towne, and K.L. Rock.
ER-Aminopeptidase I (ERAP1) trims MHC class I-presented peptides in vivo
and plays an important role in establishing immunodominance.
Proc. Natl. Acad. Sci. USA (2006) 103:9202-9207
Towne, C.F., I.A. York, J. Neijssen, M.L. Karow, A.J. Murphy, D.M. Valenzuela, G.D. Yancopoulos, J.J. Neefjes, and K.L. Rock.
Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation.
Journal of Immunology (2005) 175:6605-6614
York, I.A., E.P. Grant, A.M. Dahl, and K.L. Rock.
A mutant cell with a novel defect in MHC class I quality control.
Journal of Immunology (2005) 174:6839-6846
York, I.A., A.X. Mo, K. Lemerise, W. Zeng, Y. Shen, C.R. Abraham, T.
Saric, A.L. Goldberg, and K.L. Rock.
The cytosolic endopeptidase,
thimet oligopeptidase, destroys antigenic peptides and limits the extent
of MHC class I antigen presentation.
Immunity. (2003) 18:429-40.
York, I.A., S.-C. Chang, T. Saric, J.A. Keys, J.M. Favreau, A.L. Goldberg,
and K.L. Rock.
The ER aminopeptidase, ERAP1, enhances or limits
antigen presentation by trimming epitopes to 8-9 residues.
Nature
Immunology (2002) 3:1177-1184
Saric, T., S.-C. Chang, A. Hattori, I.A. York, S. Markant, K.L. Rock, M.
Tsujimoto, and A.L. Goldberg.
ERAP1, an interferon-induced
aminopeptidase in the endoplasmic reticulum, that trims precursors to MHC
class I-presented peptides.
Nature Immunology (2002)
3:1169-1176
Russell, H.I., I.A. York, K.L. Rock, and J.J. Monaco.
Class II
antigen processing defects in two H2d mouse cell lines are caused by point
mutations in the H2-DMa gene.
Eur. J. Immunol. (1999)
29:905-911
Tomazin, R., A. Hill, P. Jugovic, I. York, P. van Endert, H. Ploegh, D. Andrews, and
D. Johnson.
Stable binding of the herpes virus ICP47 protein to the
peptide binding domain of TAP.
EMBO
Journal (1996) 15:3256-3266
Hill, A., P. Jugovic, I. York, G. Russ, J. Bennink, J. Yewdell, H. Ploegh,
and D. Johnson.
Herpes simplex virus turns off the TAP to evade host immunity.
Nature (1995) 375:411-415
Levatte, M.A., L.C. Weaver, J.R. Smiley, I.A. York, D.C. Johnson, and G.A.
Dekaban.
Delivery of a foreign gene to sympathetic preganglionic neurons using
recombinant herpes simplex virus.
Neuroscience (1995) 66:737-750
York, I.A., C. Roop, D.W. Andrews, S.R. Riddell, F.L. Graham, and D.C.
Johnson.
A cytosolic herpes simplex virus protein inhibits antigen presentation to
CD8+ T lymphocytes.
Cell (1994) 77:525-535
York, I.A., and D.C. Johnson.
Direct contact with herpes simplex virus-infected cells results in
inhibition of lymphokine-activated killer cells because of cell-to-cell
spread of virus.
Journal of Infectious Diseases (1993)
168:1127-1131
York, I.A., and J. Thorsen.
Evaluation of a subunit vaccine for bovine adenovirus serotype 3.
American Journal Veterinary Research (1992) 53:180-183
K.L. Rock, I.A. York, and A.L. Goldberg.
Post-proteasomal antigen processing for MHC class I presentation.
Nature Immunology (2004) 5:670-677
Rock, K.L., I.A. York, T. Saric, and A.L. Goldberg.
Protein
degradation and the generation of MHC class I-presented peptides.
Advances in Immunology (2002) 80:1-70
York, I.A., A.L. Goldberg, X.Y. Mo, and K.L. Rock.
Proteolysis
and class I major histocompatibility complex antigen presentation.
Immunological Reviews (1999) 172:49-66
York, I.A.
Immune evasion strategies of the herpesviruses.
Chemistry & Biology (1996) 3:331-335
York, I.A., and K.L. Rock.
Antigen processing and presentation by class I MHC.
Annual
Review of Immunology (1996) 14:369-396
York, I.A., and D.C. Johnson.
Inhibition of humoral and cellular immune recognition by herpes simplex
viruses.
IN: Viroceptors, Virokines, and Related Immune Modulators Encoded by DNA
Viruses. Ed. G. McFadden. Austin: R.G. Landes Co., 1995:89-110