This is not to say that there is no setting, no plot, and no characterization. These elements are woven into the encyclopedia-form with extraordinary subtlety. The setting of the novel isn’t a physical landscape but a conceptual one. Unusually for what purports to be a dictionary of madness, the story proper begins with a discussion of neurological impairments: autism, Rett’s disorder, “intellectual disability”. The scene this prologue sets is one of a profoundly bleak view of human beings; one in which we hobble across an empty field, crippled by blind and mechanical forces whose workings are entirely beyond any understanding. This vision of humanity’s predicament has echoes of Samuel Beckett at some of his more nihilistic moments—except that Beckett allows his tramps to speak for themselves, and when they do they’re often quite cheerful. The sufferers of DSM-5, meanwhile, have no voice; they’re only interrogated by a pitiless system of categorizations with no ability to speak back. As you read, you slowly grow aware that the book’s real object of fascination isn’t the various sicknesses described in its pages, but the sickness inherent in their arrangement.

Sam Kriss, “Book of Lamentations”